AN ASSOCIATION OF AQUAPORIN-4 WITH THE IMMUNOREGULATION OF LIVER PATHOLOGY IN MICE INFECTED WITH SCHISTOSOMA JAPONICUM

An association of Aquaporin-4 with the immunoregulation of liver pathology in mice infected with Schistosoma japonicum

Abstract Background Schistosomiasis is a chronic parasitic disease that affects approximately 200 million people.In Schistosomiasis japonica and mansoni, parasite eggs were trapped in host liver and stimulated the CD4+T cell responses to regulate the formation of the granulomas.Subsequently, excessive granulomatous response in some heavily, and/or

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